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apxl蛋白抗体
产品介绍 靶标: shroom2 产品别名: apxl; hsapxl; shroom2; shroom family member 2; shroom family member 2; protein shroom2; apx homolog of xenopus; apical-like protein; apxl蛋白; 背景信息: shroom family member 2 is a protein that in humans is encoded by the shroom2 gene. this gene represents the human homolog of xenopus laevis apical protein (apx) gene, which is implicated in amiloride-sensitive sodium channel activity. it is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. this gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. alternatively spliced transcript variants have been found for this gene. 宿主:rbt |
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